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Hard Tissue Preparation

Experimental implant research is the implantation of small implants in the bones of animals. The purpose is to examine how a given treatment effects the fixation of an implant. The fixation of an implant can, among others, be illustrated by the use of ”biomechanical push-out test” and ”histomorphometry”. In order to execute these tests, the bones containing the implants have to go through a time-consuming preparation:

The implant bone block is divided in two by means of the Exact bone saw. Half of the block is immediately frozen to -20°C and saved for later use in the "biomechanical push-out test”. The other half is dehydrated in alcohol, colored with basic fusin, and embedded in plastic (polymethylmetacrylate). When embedded, 20-30 µm thin slices are cut off the implant bone block. These slices are used for ”histomorphometric” analysis.

The preparation and cutting of bone containing implants is a technically demanding procedure performed by experienced laboratory technicians at the Orthopaedic Research Lab.

 
Band Saw

Exact Apparatebau
2000 Nordenstadt
Germany

 
Kalender

Publikationer
Effects of supervised exercise compared to non-supervised exercise early after total hip replacement on patient-reported function, pain, health-related quality of life and performance-based function - a systematic review and meta-analysis of randomized controlled trials.
Hansen S, Aaboe J, Mechlenburg I, Overgaard S, Mikkelsen LR.
Association between periacetabular osteotomy and hip dysplasia among relatives: a cross-sectional study.
Simonsen PO, Hertz JM, Søballe K, Mechlenburg I.
Are patients with knee osteoarthritis and patients with knee joint replacement as physically active as healthy persons?
Daugaard R, Tjur M, Sliepen M, Lipperts M, Grimm B, Mechlenburg I.
Ortopædkirurgisk Forskning Aarhus Universitetshospital Tage-Hansens Gade 2 Bygning 9A 8000 Aarhus C Tel: +45 7846 7471
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